Long-term re-intervention after USgHIFU and prediction of NPVR in different ages of patients with uterine fibroids

作者全名："Li, Shuang; Ma, Wang-wa; Yang, Mei-Jie; Deng, Yong-Bin; Hu, Liang; Chen, Jin-Yun"

作者地址："[Li, Shuang; Ma, Wang-wa; Hu, Liang; Chen, Jin-Yun] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China; [Yang, Mei-Jie] Chongqing Med Univ, Coll Med Informat, Chongqing, Peoples R China; [Deng, Yong-Bin] Chongqing Haifu Hosp, Dept Gynecol, Chongqing, Peoples R China; [Hu, Liang; Chen, Jin-Yun] Chongqing Med Univ, Affiliated Hosp 1, Ultrasound Ablat Ctr, Chongqing, Peoples R China"

通信作者："Hu, L; Chen, JY (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China.; Hu, L; Chen, JY (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Ultrasound Ablat Ctr, Chongqing, Peoples R China."

来源：INTERNATIONAL JOURNAL OF HYPERTHERMIA

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001146824100001

JCR分区：Q2

影响因子：3.1

年份：2024

卷号：41

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Ultrasound-guided high intensity focused ultrasound (USgHIFU); uterine fibroids; non-perfusion volume ratio (NPVR); re-intervention; age

摘要："Objective: Long-term re-intervention after ultrasound-guided high intensity focused ultrasound (USgHIFU) ablation was reported, and the prediction of non-perfusion volume ratio (NPVR) in differently aged patients with uterine fibroids (UFs) was explored.Materials and Methods: Patients with UFs who underwent USgHIFU ablation from January 2012 to December 2019 were enrolled and divided into < 40-year-old and >= 40-year-old groups. Cox regression was used to analyze the influencing factors of re-intervention rate, and receiver operating characteristic (ROC) curve was used to analyze the correlation between NPVR and re-intervention rate.Results: A total of 2141 patients were enrolled, and 1558 patients were successfully followed up. The 10-year cumulative re-intervention rate was 21.9%, and the < 40-year-old group had a significantly higher rate than the >= 40-year-old group (30.8% vs. 19.1%, p < 0.001). NPVR was an independent risk factor in both two groups. When the NPVR reached 80.5% in the < 40-year-old group and 75.5% in the >= 40-year-old group, the risk of long-term re-intervention was satisfactory.Conclusion: The long-term outcome of USgHIFU is promising. The re-intervention rate is related to NPVR in differently aged patients. Young patients need a high NPVR to reduce re-intervention risk."

基金机构："Natural Science Foundation Project of Chongqing [cstc2021jcyj-msxmX0514, CSTB2022NSCQMSX0140]"

基金资助正文：This study was supported by the Natural Science Foundation Project of Chongqing [grant number: cstc2021jcyj-msxmX0514 and CSTB2022NSCQMSX0140.]