Trajectories of antidepressant use before and after union dissolution and re-partnering in later life: a prospective total population register-based cohort study

作者全名："Hu, Yaoyue; Metsa-Simola, Niina; Malmberg, Satu; Martikainen, Pekka"

作者地址："[Hu, Yaoyue] Chongqing Med Univ, Sch Publ Hlth, Chongqing, Peoples R China; [Metsa-Simola, Niina; Malmberg, Satu; Martikainen, Pekka] Univ Helsinki, Fac Social Sci, Populat Res Unit, Helsinki, Finland; [Martikainen, Pekka] Max Planck Inst Demog Res, Rostock, Mecklenburg Vor, Germany; [Martikainen, Pekka] Max Planck Univ, Helsinki Ctr Social Inequal Populat Hlth, Helsinki, Finland"

通信作者："Hu, YY (通讯作者)，Chongqing Med Univ, Sch Publ Hlth, Chongqing, Peoples R China."

来源：JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

ESI学科分类：SOCIAL SCIENCES, GENERAL

WOS号：WOS:001161651800001

JCR分区：Q1

影响因子：6.3

年份：2024

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：DEPRESSION; GERONTOLOGY; SOCIAL SCIENCES

摘要："Background Grey divorce and later remarriage have become increasingly common in high-income countries, but previous evidence on their impacts on mental health is scarce. Even less is known about the effects of non-marital separation and re-partnering in later life.Methods Using Finnish registry data from 1996 to 2018 on 228 644 individuals aged 50-70 in 2000-2014, trajectories of antidepressant (AD) use 4 years before and 4 years after divorce, non-marital separation, bereavement and subsequent re-partnering were examined using individual fixed-effects (FE) linear probability models.Results In adjusted FE models, for both genders AD use increased during the 4 years before divorce (men: 5.00 percentage points (95% CI 4.50 to 5.50); women: 6.96 (95% CI 6.34 to 7.59)), non-marital separation (men: 3.20 (95% CI 2.72 to 3.69); women: 5.98 (95% CI 5.30 to 6.66)) and bereavement (men: 4.53 (95% CI 3.97 to 5.09); women: 5.64 (95% CI 5.25 to 6.04)), with the increase accelerating immediately before the event. AD use gradually declined after union dissolution, after which it stabilised on a persistently higher level compared with pre-dissolution. Re-partnering was only associated with a small and transitory reduction in AD use (0.1-1.5 percentage points). The increases in AD use associated with union dissolution were larger in women than in men, whereas the small reductions in AD use associated with re-partnering were particularly short-lived among women.Conclusions Our results suggest that union dissolution in later life is associated with large and persistent increases in AD use, whereas the reductions associated with re-partnering are limited both in magnitude and duration."

基金机构："Future Medical Youth Innovation Team Development Support Programme of Chongqing Medical University [W0103]; European Research Council under the European Union [101019329]; Strategic Research Council (SRC) within the Academy of Finland grants for ACElife [352543-352572]; LIFECON [308247]; Jane and Aatos Erkko Foundation; Max Planck Society; University of Helsinki; Cities of Helsinki, Vantaa and Espoo"

基金资助正文："YH was supported by the Future Medical Youth Innovation Team Development Support Programme of Chongqing Medical University (#W0103). PM was supported by the European Research Council under the European Union's Horizon 2020 Research and Innovation Programme (#101019329), the Strategic Research Council (SRC) within the Academy of Finland grants for ACElife (#352543-352572) and LIFECON (#308247), and grants to the Max Planck - University of Helsinki Center from the Jane and Aatos Erkko Foundation, the Max Planck Society, University of Helsinki, and Cities of Helsinki, Vantaa and Espoo."