The maternal phylogenetic insights of Yunnan Miao group revealed by complete mitogenomes

作者全名："Chen, Chong; Guo, Yuxin; Fang, Yating; Shi, Jianfeng; Meng, Haotian; Qu, Li; Zhang, Xingru; Zhu, Bofeng"

作者地址："[Chen, Chong; Guo, Yuxin; Shi, Jianfeng; Meng, Haotian; Zhang, Xingru; Zhu, Bofeng] Xi An Jiao Tong Univ, Coll Stomatol, Key Lab Shaanxi Prov Craniofacial Precis Med Res, Xian 710004, Peoples R China; [Chen, Chong] Chongqing Med Univ, Fac Basic Med Sci, Dept Forens Med, Chongqing 400016, Peoples R China; [Fang, Yating] Anhui Med Univ, Sch Basic Med Sci, Hefei 230031, Anhui, Peoples R China; [Qu, Li] Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Rheumatol & Immunol, Xian 710004, Shaanxi, Peoples R China; [Zhang, Xingru; Zhu, Bofeng] Xi An Jiao Tong Univ, Hlth Sci Ctr, Coll Forens Med, Xian 710061, Peoples R China; [Zhu, Bofeng] Southern Med Univ, Sch Forens Med, Dept Forens Genet, Multiom Innovat Res Ctr Forens Identificat, Guangzhou 510515, Peoples R China"

通信作者："Zhu, BF (通讯作者)，Xi An Jiao Tong Univ, Coll Stomatol, Key Lab Shaanxi Prov Craniofacial Precis Med Res, Xian 710004, Peoples R China.; Zhu, BF (通讯作者)，Xi An Jiao Tong Univ, Hlth Sci Ctr, Coll Forens Med, Xian 710061, Peoples R China.; Zhu, BF (通讯作者)，Southern Med Univ, Sch Forens Med, Dept Forens Genet, Multiom Innovat Res Ctr Forens Identificat, Guangzhou 510515, Peoples R China."

来源：GENE

ESI学科分类：MOLECULAR BIOLOGY & GENETICS

WOS号：WOS:001167684900001

JCR分区：Q2

影响因子：3.5

年份：2024

卷号：901

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："The Miao group is one of the representative Hmong-Mien-speaking populations and primarily scattered in southern China and Southeast Asia, which has experienced massive migrations in history and thus forms distinctive evolutionary genetics. Yet, the genetic explorations of Miao group are relatively limited based on complete mitochondrial genome (mitogenome), especially for the Miao group from Yunnan Province (YNM). Here, we sequenced complete mitogenomes of 132 Miao individuals from Yunnan Province using massively parallel sequencing method. Total 132 Miao individuals could be allocated to 119 various haplotypes, which were mainly dominated by haplogroups prevalent in southern East Asia (B, F, M7 and R9), and rarely occupied by northern lineages (A, D, G and M8). In order to dissect the genetic background of YNM more comprehensively, we introduced 99 published population data with 7135 complete mitochondrial sequences for population genetic comparisons. YNM exhibited closer genetic relationships with Hmong-Mien, Tai-Kadai, Sino-Tibetan and Austroasiatic populations, especially for Hmong-Mien populations; we further speculated that Miao group might have certain direct or indirect gene exchanges with ancient Baiyue groups. Several maternal lineages, such as B5a1c1a, F1g1, B4a5 and D4e1a3, were found to be specifically shared by YNM and other Hmong-Mien populations, and these matrilineal expansions occurred roughly during the Neolithic period. Eventually, according to the population dynamic analyses of YNM, the population size began to emerge recovery -1-0.5 kya after a longterm population reduction -1-5 kya, during which the B5a1c1a haplogroup manifested relatively apparent lineage expansion."

基金机构："Major Program of the National Natural Science Foundation of China [82293650, 82293652]; Chongqing post-doctoral Science Foundation [CSTB2023NSCQ-BHX0161]; Natural Science Basic Research Program of Shaanxi Province [2022JQ-926]"

基金资助正文："This study was funded by the Major Program of the National Natural Science Foundation of China (82293650, 82293652) , Chongqing post-doctoral Science Foundation (CSTB2023NSCQ-BHX0161) , and Natural Science Basic Research Program of Shaanxi Province (2022JQ-926) . We certify that this manuscript has not been submitted or accepted for publication elsewhere, nor have we assigned any right or interest in the manuscript to any third party. We certify that our institution has approved any investigation involving humans or human material or data, and that the investigation was conducted in accordance with humane and ethical research principles. This study was conducted with the approval of the Ethics Committee of Xi'an Jiaotong University Health Science Center (approval number: 2019-1039; 2021-8) . We have abided by the statement of ethical standards for manuscripts submitted to Gene."