What can we learn from treatments of oral lichen planus?

作者全名："Wu, Tingting; Bai, Yang; Jing, Yin; Chen, Fangchun"

作者地址："[Wu, Tingting; Bai, Yang; Jing, Yin; Chen, Fangchun] Chongqing Med Univ, Stomatol Hosp, Chongqing, Peoples R China; [Wu, Tingting; Bai, Yang; Jing, Yin; Chen, Fangchun] Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing, Peoples R China; [Wu, Tingting; Bai, Yang; Jing, Yin; Chen, Fangchun] Chongqing Municipal Key Lab Oral Biomed Engn Highe, Chongqing, Peoples R China"

通信作者："Chen, FC (通讯作者)，Chongqing Med Univ, Stomatol Hosp, Chongqing, Peoples R China.; Chen, FC (通讯作者)，Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing, Peoples R China.; Chen, FC (通讯作者)，Chongqing Municipal Key Lab Oral Biomed Engn Highe, Chongqing, Peoples R China."

来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

ESI学科分类：MICROBIOLOGY

WOS号：WOS:001173872000001

JCR分区：Q2

影响因子：5.7

年份：2024

卷号：14

期号：　

开始页：　

结束页：　

文献类型：Review

关键词：oral lichen planus; erosive type; pharmacological treatment; nonpharmacological treatment; microbes

摘要："Oral lichen planus (OLP), a T-lymphocyte-mediated disease of the oral mucosa, has a complex pathogenesis that involves a number of factors. The disease is characterized by recurrent episodes and requires continuous follow up, and there is no curative treatment available. Erosive lichen planus, among others, has a risk of malignant transformation and requires standardized treatment to control its progression. Different clinical subtypes of oral lichen planus require appropriate treatment. Pharmacological treatments are the most widely available and have the greatest variety of options and a number of novel pharmacological treatments are presented as highlights, including JAK enzyme inhibitors. The second is photodynamic therapy, which is the leading physiological treatment. In addition, periodontal treatment and psychological treatment should not be neglected. In this review, we briefly discuss the most recent developments in therapies for oral lichen planus after summarizing the most widely used clinical treatments, aiming to provide different proposals for future clinical treatment."

基金机构：Joint project of Chongqing Health Commission and Science and Technology Bureau [2020MSXM005]

基金资助正文："The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Joint project of Chongqing Health Commission and Science and Technology Bureau (2020MSXM005)."