The Influence of Genetic and Environmental Factors on Anxiety among Chinese Adolescents: A Twin Study
作者全名："Wang, Fangyi; Ma, Xingshun; Zhao, Liansheng; Li, Tao; Fu, Yixiao; Zhu, Wenfen"
作者地址："[Wang, Fangyi; Zhu, Wenfen] Chongqing Med Univ, Sch Nursing, Chongqing, Peoples R China; [Ma, Xingshun] First Hosp Yulin, Dept Neurol, Yulin, Peoples R China; [Zhao, Liansheng] Sichuan Univ, West China Hosp, Mental Hlth Ctr, Chengdu, Peoples R China; [Fu, Yixiao] Chongqing Med Univ, Dept Psychiat, Affiliated Hosp 1, Chongqing, Peoples R China; [Li, Tao] Zhejiang Univ, Hangzhou Peoples Hosp 7, Affiliated Mental Hlth Ctr, Sch Med, Hangzhou, Peoples R China; [Zhu, Wenfen] Chongqing Med Univ, Med Data Res Inst, Chongqing, Peoples R China; [Zhu, Wenfen] Chongqing Med Univ Nursing, Chongqing, Peoples R China; [Li, Tao] Zhejiang Univ, Hangzhou Peoples Hosp 7, Affiliated Mental Hlth Ctr, Sch Med, Hangzhou, Zhejiang, Peoples R China"
通信作者："Fu, YX (通讯作者)，Chongqing Med Univ, Dept Psychiat, Affiliated Hosp 1, Chongqing, Peoples R China.; Zhu, WF (通讯作者)，Chongqing Med Univ Nursing, Chongqing, Peoples R China.; Li, T (通讯作者)，Zhejiang Univ, Hangzhou Peoples Hosp 7, Affiliated Mental Hlth Ctr, Sch Med, Hangzhou, Zhejiang, Peoples R China."
来源：JOURNAL OF GENETIC PSYCHOLOGY
ESI学科分类：PSYCHIATRY/PSYCHOLOGY
WOS号：WOS:001178173800001
JCR分区：Q3
影响因子：1.6
年份：2024
卷号：
期号：
开始页：
结束页：
文献类型：Article; Early Access
关键词：Anxiety; genetic; environmental; adolescent; twins
摘要："This study explored the influence of genetic and environmental factors on adolescent anxiety. Ninety-eight monozygotic and dizygotic twins from Chongqing, China (aged 15-18 years) were assessed for anxiety with the Self-Rating Anxiety Scale (SAS). The Parenting Styles and Dimensions Questionnaire (PSDQ) and Strengths and Difficulties Questionnaire (SDQ) were applied to assess environmental factors. Venous blood was drawn from the twins for zygosity determination. Structural equation modeling was performed to evaluate the effects of additive genetic factors (A), common environmental factors (C), and individual-specific environmental factors (E) on adolescent anxiety. The estimates of A and E on adolescent anxiety were 0.34 (95% CI = 0.12-0.53) and 0.66 (95% CI:0.47-0.89), respectively. The environment played an important role in adolescent anxiety. Adolescent anxiety was significantly positively correlated with peer relations (r = 0.606, p < 0.05) and negatively correlated with prosocial behavior (r = 0.207, p < 0. 05). No sex differences were observed. Adolescent anxiety was influenced by both genetic and environmental factors. The individual-specific environmental factors played an important role. Consideration of these variables will facilitate the targeted and individualized implementation of specific interventions for adolescent anxiety."
基金机构："Intelligent Medicine Research Project of Chongqing Medical University [ZHYX202218]; Chongqing Social Science Planning Social Organization Project [2022sz11]; Senior Medical Talents Program of Chongqing for Yong and Middle-aged; Program for Youth Innovation in Future Medicine, Chongqing Medical University [w0107]; Natural Science Foundation Project of Chongqing [CSTB2022NSCQ-MSX0121]; Scientific Research Program, Chongqing Medical University of Nursing [20230302]"
基金资助正文："This work was supported by the following organizations and projects: Intelligent Medicine Research Project of Chongqing Medical University (ZHYX202218); Chongqing Social Science Planning Social Organization Project (2022sz11); Senior Medical Talents Program of Chongqing for Yong and Middle-aged; Program for Youth Innovation in Future Medicine, Chongqing Medical University (w0107); Natural Science Foundation Project of Chongqing (CSTB2022NSCQ-MSX0121); Scientific Research Program, Chongqing Medical University of Nursing (20230302)."
