Manipulating the Piezoelectric Response of Amino Acid-Based Assemblies by Supramolecular Engineering

作者全名："Wang, Yuehui; Liu, Shuaijie; Li, Lingling; Li, Hui; Yin, Yuanyuan; Rencus-Lazar, Sigal; Guerin, Sarah; Ouyang, Wengen; Thompson, Damien; Yang, Rusen; Cai, Kaiyong; Gazit, Ehud; Ji, Wei"

作者地址："[Wang, Yuehui; Liu, Shuaijie; Cai, Kaiyong; Ji, Wei] Chongqing Univ, Coll Bioengn, Key Lab Biorheol Sci & Technol, Minist Educ, Chongqing 400044, Peoples R China; [Li, Lingling] Shanghai Jiao Tong Univ, Instrumental Anal Ctr, Shanghai 200240, Peoples R China; [Li, Hui] Xian Modern Chem Res Inst, Xian 710065, Peoples R China; [Yin, Yuanyuan] Chongqing Med Univ, Stomatol Hosp, Chongqing Key Lab Oral Dis & Biomed Sci, Chongqing Municipal Key Lab Oral Biomed Engn Highe, Chongqing 401147, Peoples R China; [Rencus-Lazar, Sigal; Gazit, Ehud] Tel Aviv Univ, George S Wise Fac Life Sci, Sch Mol Cell Biol & Biotechnol, IL-6997801 Tel Aviv, Israel; [Guerin, Sarah; Thompson, Damien] Univ Limerick, Bernal Inst, Dept Phys, Limerick V94 T9PX, Ireland; [Ouyang, Wengen] Wuhan Univ, Sch Civil Engn, Dept Engn Mech, Wuhan 430072, Peoples R China; [Yang, Rusen] Xidian Univ, Sch Adv Mat & Nanotechnol, Xian 710126, Peoples R China; [Gazit, Ehud] Tel Aviv Univ, Iby & Aladar Fleischman Fac Engn, Dept Mat Sci & Engn, IL-6997801 Tel Aviv, Israel"

通信作者："Cai, KY; Ji, W (通讯作者)，Chongqing Univ, Coll Bioengn, Key Lab Biorheol Sci & Technol, Minist Educ, Chongqing 400044, Peoples R China.; Gazit, E (通讯作者)，Tel Aviv Univ, George S Wise Fac Life Sci, Sch Mol Cell Biol & Biotechnol, IL-6997801 Tel Aviv, Israel.; Gazit, E (通讯作者)，Tel Aviv Univ, Iby & Aladar Fleischman Fac Engn, Dept Mat Sci & Engn, IL-6997801 Tel Aviv, Israel."

来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ESI学科分类：CHEMISTRY

WOS号：WOS:001021444300001

JCR分区：Q1

影响因子：14.4

年份：2023

卷号：145

期号：28

开始页：15331

结束页：15342

文献类型：Article

关键词：　

摘要："Variation in the molecular architecture significantlyaffects theelectronic and supramolecular structure of biomolecular assemblies,leading to dramatically altered piezoelectric response. However, relationshipbetween molecular building block chemistry, crystal packing and quantitativeelectromechanical response is still not fully understood. Herein,we systematically explored the possibility to amplify the piezoelectricityof amino acid-based assemblies by supramolecular engineering. We showthat a simple change of side-chain in acetylated amino acids leadsto increased polarization of the supramolecular arrangements, resultingin significant enhancement of their piezoelectric response. Moreover,compared to most of the natural amino acid assemblies, chemical modificationof acetylation increased the maximum piezoelectric tensors. The predictedmaximal piezoelectric strain tensor and voltage constant of acetylatedtryptophan (L-AcW) assemblies reach 47 pm V-1 and1719 mV m/N, respectively, comparable to commonly used inorganic materialssuch as bismuth triborate crystals. We further fabricated an L-AcWcrystal-based piezoelectric power nanogenerator that produces a highand stable open-circuit voltage of over 1.4 V under mechanical pressure.For the first time, the illumination of a light-emitting diode (LED)is demonstrated by the power output of an amino acid-based piezoelectricnanogenerator. This work presents the supramolecular engineering towardthe systematic modulation of piezoelectric response in amino acid-basedassemblies, facilitating the development of high-performance functionalbiomaterials from simple, readily available, and easily tailored buildingblocks."

基金机构："National Natural Science Foundation of China [52103148]; Returning Overseas Scholar Innovation Program [cx2021055]; Chongqing University; Joint NSFC-ISF Grant [3145/19]; Joint NSF-BSF Grant [2020752]; Science Foundation Ireland (SFI) [12/RC/2275_P2, 21/PATH-S/9737]"

基金资助正文："This work was supported by the National Natural Science Foundation of China (no. 52103148), Returning Overseas Scholar Innovation Program (no. cx2021055), the Start-up Funding from Chongqing University, Joint NSFC-ISF Grant (no. 3145/19), Joint NSF-BSF Grant (no. 2020752), and Science Foundation Ireland (SFI) under award numbers 12/RC/2275_P2 and 21/PATH-S/9737."