Longitudinal patterns of patient-reported sleep disturbances after surgery for lung cancer

作者全名："Pu, Yang; Xu, Wei; Dai, Wei; Wei, Xing; Yu, Hongfan; Yu, Qingsong; Su, Xueyao; Gong, Ruoyan; Zhang, Yubo; Shi, Qiuling"

作者地址："[Pu, Yang; Xu, Wei; Su, Xueyao; Gong, Ruoyan; Shi, Qiuling] Chongqing Med Univ, Res Ctr Med & Social Dev, Sch Publ Hlth, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China; [Dai, Wei; Wei, Xing] Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Sichuan Canc Ctr, Dept Thorac Surg, Chengdu, Sichuan, Peoples R China; [Yu, Hongfan; Zhang, Yubo; Shi, Qiuling] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China; [Yu, Qingsong] Chengdu Ctr Dis Control & Prevent, Chengdu, Sichuan, Peoples R China; [Shi, Qiuling] Univ Elect Sci & Technol China, Sichuan Canc Hosp, Ctr Canc Prevent Res, Chengdu, Sichuan, Peoples R China"

通信作者："Shi, QL (通讯作者)，Chongqing Med Univ, Res Ctr Med & Social Dev, Sch Publ Hlth, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China.; Shi, QL (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China.; Shi, QL (通讯作者)，Univ Elect Sci & Technol China, Sichuan Canc Hosp, Ctr Canc Prevent Res, Chengdu, Sichuan, Peoples R China."

来源：SLEEP AND BREATHING

ESI学科分类：NEUROSCIENCE & BEHAVIOR

WOS号：WOS:001023885700001

JCR分区：Q3

影响因子：2.1

年份：2023

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期号：　

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文献类型：Article; Early Access

关键词：Lung cancer; Group-based trajectory model; Sleep disturbance; Pain

摘要："PurposeThe purpose of this study was to identify longitudinal heterogeneous trajectories of sleep status, adjusted for the effect of pain over time, among patients who had surgery for lung cancer and to quantify how disturbed sleep in the hospital affects functional recovery after discharge.MethodsWe included patients from a surgical cohort (CN-PRO-Lung 1). All patients reported symptoms using the MD Anderson Symptom Inventory-Lung Cancer (MDASI-LC) daily during postoperative hospitalization. Group-based dual trajectory modeling was used to investigate trajectories of disturbed sleep and pain during the first 7 days of postoperative hospitalization. Cox regression was used to compare the recovery of walking ability between the different sleep trajectories.ResultsAmong 421 patients, disturbed sleep trajectories comprised low (31%), moderate (52%), and high (17%) groups. The surgical approach and number of chest tubes were associated with pain, and the number of chest tubes was also associated with sleep disturbances (OR = 1.99; 95% CI: 1.08-3.67). Recovery of walking ability after discharge was significantly slower in the high (median days = 16; 95% CI: 5-NA) and moderate disturbed sleep trajectory groups (median days = 5; 95%CI: 4-6) than in the low group (median days = 3; 95% CI: 3-4).ConclusionChanges in disturbed sleep among patients with lung cancer followed three distinct trajectories over the first 7 days of hospitalization after surgery. Dual trajectory analyses highlighted the high concordance between specific trajectories of disturbed sleep and pain. Patients at high sleep disturbance and high levels of pain may benefit from appropriate interventions for both symptoms in combination with the patient's surgical approach and the number of chest tubes."

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