"Global, Regional, and National Advances Toward the Management of Rheumatic Heart Disease Based on the Global Burden of Disease Study 2019"

作者全名："Ruan, Renjie; Liu, Xiaozhu; Zhang, Yunrui; Tang, Ming; He, Bo; Zhang, Qing-Wei; Shu, Tingting"

作者地址："[Ruan, Renjie; Zhang, Yunrui] Wenzhou Med Univ, Affiliated Hosp 3, Dept Cardiol, Wenzhou, Zhejiang, Peoples R China; [Liu, Xiaozhu] Chongqing Med Univ, Affiliated Hosp 2, Dept Cardiol, Chongqing, Peoples R China; [Tang, Ming; He, Bo; Shu, Tingting] Third Mil Med Univ, Army Med Univ, Chongqing, Peoples R China; [Zhang, Qing-Wei] Shanghai Jiao Tong Univ, Shanghai Inst Digest Dis, Sch Med, Div Gastroenterol Hepatol,Key Lab Gastroenterol &, Shanghai, Peoples R China; [Zhang, Qing-Wei; Shu, Tingting] 30 Gaotanyan St, Chongqing 400038, Peoples R China"

通信作者："Zhang, QW; Shu, TT (通讯作者)，30 Gaotanyan St, Chongqing 400038, Peoples R China."

来源：JOURNAL OF THE AMERICAN HEART ASSOCIATION

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001024292700047

JCR分区：Q1

影响因子：5

年份：2023

卷号：12

期号：13

开始页：　

结束页：　

文献类型：Article

关键词：disability-adjusted life-years; Global Burden of Disease 2019; mortality; prevalence; rheumatic heart disease

摘要："BackgroundPopulation growth, aging, and major alterations in epidemiologic trends inadvertently modulate the status of rheumatic heart disease (RHD) epidemiology. This investigation predicted RHD burden pattern and temporal trends to provide epidemiologic evidence. Methods and ResultsPrevalence, mortality, and disability-adjusted life-years data for RHD were obtained from the GBD (Global Burden of Disease) study. We performed decomposition analysis and frontier analysis to assess variations and burden in RHD from 1990 to 2019. In 2019, there were >40.50 million RHD cases worldwide, along with nearly 0.31 million RHD-related deaths and 10.67 million years of healthy life lost to RHD. The RHD burden was commonly concentrated within lower sociodemographic index regions and countries. RHD primarily affects women (22.52 million cases in 2019), and the largest age-specific prevalence rate was at 25 to 29 years in women and 20 to 24 years in men. Multiple reports demonstrated prominent downregulation of RHD-related mortality and disability-adjusted life-years at the global, regional, and national levels. Decomposition analysis revealed that the observed improvements in RHD burden were primarily due to epidemiological alteration; however, it was negatively affected by population growth and aging. Frontier analysis revealed that the age-standardized prevalence rates were negatively linked to sociodemographic index, whereas Somalia and Burkina Faso, with lower sociodemographic index, showed the lowest overall difference from the frontier boundaries of mortality and disability-adjusted life-years. ConclusionsRHD remains a major global public health issue. Countries such as Somalia and Burkina Faso are particularly successful in managing adverse outcomes from RHD and may serve as a template for other countries."

基金机构：　

基金资助正文：