Surface modifications of biomaterials in different applied fields

作者全名："Hu, Xi; Wang, Teng; Li, Faqi; Mao, Xiang"

作者地址："[Hu, Xi; Wang, Teng; Li, Faqi; Mao, Xiang] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing 400016, Peoples R China; [Hu, Xi; Wang, Teng; Li, Faqi; Mao, Xiang] Chongqing Med Univ, Coll Biomed Engn, Chongqing Key Lab Biomed Engn, Chongqing 400016, Peoples R China"

通信作者："Li, FQ; Mao, X (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing 400016, Peoples R China.; Li, FQ; Mao, X (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, Chongqing Key Lab Biomed Engn, Chongqing 400016, Peoples R China."

来源：RSC ADVANCES

ESI学科分类：CHEMISTRY

WOS号：WOS:001025126200001

JCR分区：Q2

影响因子：3.9

年份：2023

卷号：13

期号：30

开始页：20495

结束页：20511

文献类型：Review

关键词：　

摘要："Biomaterial implantation into the human body plays a key role in the medical field and biological applications. Increasing the life expectancy of biomaterial implants, reducing the rejection reaction inside the human body and reducing the risk of infection are the problems in this field that need to be solved urgently. The surface modification of biomaterials can change the original physical, chemical and biological properties and improve the function of materials. This review focuses on the application of surface modification techniques in various fields of biomaterials reported in the past few years. The surface modification techniques include film and coating synthesis, covalent grafting, self-assembled monolayers (SAMs), plasma surface modification and other strategies. First, a brief introduction to these surface modification techniques for biomaterials is given. Subsequently, the review focuses on how these techniques change the properties of biomaterials, and evaluates the effects of modification on the cytocompatibility, antibacterial, antifouling and surface hydrophobic properties of biomaterials. In addition, the implications for the design of biomaterials with different functions are discussed. Finally, based on this review, it is expected that the biomaterials have development prospects in the medical field."

基金机构："Chongqing Municipal Natural Science Foundation [CSTB2022NSCQ-MSX0113]; Scientific Foundation Project of Chongqing Education Commission [KJQN201900436]; National Natural Science Foundation of China [81127901, 12074051]"

基金资助正文："This work was supported by the Chongqing Municipal Natural Science Foundation: CSTB2022NSCQ-MSX0113; Scientific Foundation Project of Chongqing Education Commission: KJQN201900436; National Natural Science Foundation of China: 81127901, 12074051."