Treatment of humeral shaft fractures with different treatment methods: a network meta-analysis of randomized controlled trials

作者全名："Qiu, Hao; Liu, Yuting; Chen, Yu; Weng, Zheng; Liu, Dun; Dong, Jing; Lu, Minpeng"

作者地址："[Qiu, Hao; Chen, Yu; Weng, Zheng; Liu, Dun] Ninth Peoples Hosp Chongqing, Trauma Orthoped & Hand Foot Ankle Surg, Chongqing 400700, Peoples R China; [Liu, Yuting] Ninth Peoples Hosp Chongqing, Dept Endocrinol, Chongqing 400700, Peoples R China; [Dong, Jing] Chongqing Med & Pharmaceut Coll, Dept Clin Med, Chongqing 401331, Peoples R China; [Lu, Minpeng] Chongqing Med Univ, Affiliated Hosp 1, Dept Pain Med, Chongqing 400016, Peoples R China"

通信作者："Dong, J (通讯作者)，Chongqing Med & Pharmaceut Coll, Dept Clin Med, Chongqing 401331, Peoples R China.; Lu, MP (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Pain Med, Chongqing 400016, Peoples R China."

来源：BMC MUSCULOSKELETAL DISORDERS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001032457700003

JCR分区：Q2

影响因子：2.2

年份：2023

卷号：24

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Non-operative; Open reduction and plate osteosynthesis; Minimally invasive plate osteosynthesis; Intramedullary nail; Humeral shaft fracture; Network meta-analysis

摘要："PurposeHumeral shaft fractures (HSFs) can be treated non-operatively (Non-OP), with open reduction and plate osteosynthesis (ORPO), minimally invasive plate osteosynthesis (MIPO), or with intramedullary nails (IMN). However, the best treatment for HSFs still remains controversial.We performed a network meta-analysis to explore which should be the best method for HSFs.MethodsThe computerized search had been conducted on electronic databases PubMed, EMBASE, Cochrane Library, and Medline from the establishment of the database to the end of December 2022. The quality evaluation of the included literature had been completed by Review Manager (version 5.4.1). Stata 17.0 software (Stata Corporation, College Station, Texas, USA)was used for network meta-analysis.We included randomized controlled trials (RCTs) comparing different treatments to treating HSFs.ResultsThe pairwise comparison results demonstrated that there was no statistical difference between IMN, MIPO, Non-OP, and ORPO in terms of radial nerve injury and infection, and Non-OP presented significantly more nonunion than ORPO, IMN, and MIPO. However, no statistically significant difference between ORPO, IMN, and MIPO was discovered. The results of the network meta-analysis displayed that surface under the cumulative ranking curve (SUCRA) probabilities of IMN, MIPO, Non-OP, and ORPO in radial nerve injury were 46.5%, 66.9%, 77.3%, and 9.3%, respectively, in contrast, that in infection were 68.6%, 53.3%, 62.4%, and 15.4%, respectively, and that in nonunion were 51.7%, 93.1%, 0.7%, and 54.5%, respectively.ConclusionWe came to the conclusion that MIPO is currently the most effective way to treat HSFs."

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