Diagnosis and surgical outcomes of coarctation of the aorta in pediatric patients: a retrospective study

作者全名："Gong, Ting; Zhang, Feiyan; Feng, Lingxin; Zhu, Xu; Deng, Dan; Ran, Tingting; Li, Liling; Kong, Li; Sun, Liqun; Ji, Xiaojuan"

作者地址："[Gong, Ting] Univ Elect Sci & Technol China, Chengdu Womens & Childrens Cent Hosp, Sch Med, Dept Ultrasound, Chengdu, Peoples R China; [Gong, Ting; Zhang, Feiyan; Feng, Lingxin; Zhu, Xu; Ran, Tingting; Li, Liling; Kong, Li; Ji, Xiaojuan] Chongqing Med Univ, Dept Ultrasound, Childrens Hosp, Chongqing, Peoples R China; [Zhang, Feiyan] Chongqing Med & Pharmaceut Coll, Dept Ultrasound, Affiliated Hosp 1, Chongqing, Peoples R China; [Deng, Dan] Changsha Med Univ, Sch Med Imaging, Changsha, Peoples R China; [Sun, Liqun] Univ Toronto, Hosp Sick Children, Dept Pediat, Div Cardiol, Toronto, ON, Canada; [Ji, Xiaojuan] Chongqing Gen Hosp, Dept Ultrasound, Chongqing, Peoples R China"

通信作者："Ji, XJ (通讯作者)，Chongqing Med Univ, Dept Ultrasound, Childrens Hosp, Chongqing, Peoples R China.; Sun, LQ (通讯作者)，Univ Toronto, Hosp Sick Children, Dept Pediat, Div Cardiol, Toronto, ON, Canada.; Ji, XJ (通讯作者)，Chongqing Gen Hosp, Dept Ultrasound, Chongqing, Peoples R China."

来源：FRONTIERS IN CARDIOVASCULAR MEDICINE

ESI学科分类：　

WOS号：WOS:001042000800001

JCR分区：Q2

影响因子：2.8

年份：2023

卷号：10

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：coarctation of the aorta; congenital heart disease; transthoracic echocardiography; computed tomographic angiography; surgical outcome

摘要："BackgroundCoarctation of the aorta (CoA) is a common congenital cardiovascular malformation, and improvements in the diagnostic process for surgical decision-making are important. We sought to compare the diagnostic accuracy of transthoracic echocardiography (TTE) with computed tomographic angiography (CTA) to diagnose CoA. MethodsWe retrospectively reviewed 197 cases of CoA diagnosed by TTE and CTA and confirmed at surgery from July 2009 to August 2019. ResultsThe surgical findings confirmed that 19 patients (9.6%) had isolated CoA and 178 (90.4%) had CoA combined with other congenital cardiovascular malformations. The diagnostic accuracy of CoA by CTA was significantly higher than that of TTE (& chi;(2) = 6.52, p = 0.01). In contrast, the diagnostic accuracy of TTE for associated cardiovascular malformations of CoA was significantly higher than that of CTA (& chi;(2) = 15.36, p < 0.0001). Infants and young children had more preductal type of CoA, and PDA was the most frequent cardiovascular lesion associated with CoA. The pressure gradient was significantly decreased after the first operation, similar at 6 months, 1 year, and 3 years follow-ups by TTE. ConclusionsCTA is more accurate as a clinical tool for diagnosing CoA; however, TTE with color Doppler can better identify associated congenital cardiovascular malformations. Therefore, combining TTE and CTA would benefit clinical evaluation and management in patients suspected of CoA. TTE was valuable for post-operation follow-up and clinical management."

基金机构：National Natural Science Foundation of China [81301300]; Project of Chongqing Municipal Human Resources and Social Security Bureau [cx2019065]; Chongqing Health Commission Appropriate Technology Extension Project [2021jstg007]

基金资助正文："Funding This work was funded by the National Natural Science Foundation of China (Grant No. 81301300), Project of Chongqing Municipal Human Resources and Social Security Bureau (cx2019065), and Chongqing Health Commission Appropriate Technology Extension Project (2021jstg007)."