Edaravone administration and its potential association with a new clinical syndrome in cerebral infarction patients: Three case reports

作者全名："Yang, Liu; Xu, Xin; Wang, Liang; Zeng, Ke-Bin; Wang, Xue-Feng"

作者地址："[Yang, Liu] Chongqing Univ, Cent Hosp, Dept Neurol, Chongqing 400010, Peoples R China; [Xu, Xin; Wang, Liang; Zeng, Ke-Bin; Wang, Xue-Feng] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing 400010, Peoples R China; [Wang, Xue-Feng] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, 1 Jiankang Rd, Chongqing 400010, Peoples R China"

通信作者："Wang, XF (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, 1 Jiankang Rd, Chongqing 400010, Peoples R China."

来源：WORLD JOURNAL OF CLINICAL CASES

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001032687700016

JCR分区：Q3

影响因子：1.1

年份：2023

卷号：11

期号：19

开始页：4648

结束页：4654

文献类型：Article

关键词：Edaravone; Sudden death; Patients; Cerebral infarction; Case report

摘要："BACKGROUNDEdaravone is a widely used treatment for patients with cerebral infarction and, in most cases, edaravone-induced side effects are mild. However, edaravone-related adverse reactions have been receiving increasing attention.CASE SUMMARYWe treated three patients with acute cerebral infarction who died following treatment with edaravone. Edaravone is a widely used treatment for patients with cerebral infarction and, in most cases, edaravone-induced side effects are mild. However, edaravone-related adverse reactions have been receiving increasing attention.CONCLUSIONOur cases highlight the importance of educating clinicians regarding the new edaravone-induced clinical syndromes of cerebral infarction as potentially fatal adverse drug reactions. Considering that no laboratory or confirmatory test exists to diagnose edaravone-induced death from cerebral infarction, clinicians' knowledge is the key element in recognizing this phenomenon."

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