Life Course Socioeconomic Position and Cognitive Aging Trajectories: A Cross-National Cohort Study in China and England

作者全名:"Ruiz, Milagros; Hu, Yaoyue; Martikainen, Pekka; Bobak, Martin"

作者地址:"[Ruiz, Milagros] Univ Essex, Sch Hlth & Social Care, Colchester, England; [Ruiz, Milagros; Bobak, Martin] UCL, Res Dept Epidemiol & Publ Hlth, London, England; [Hu, Yaoyue] Chongqing Med Univ, Sch Publ Hlth & Management, Lab 1, Chongqing, Peoples R China; [Martikainen, Pekka] Univ Helsinki, Fac Social Sci, Populat Res Unit, Helsinki, Finland; [Martikainen, Pekka] Max Planck Univ Helsinki, Ctr Social Inequal Populat Hlth, Helsinki, Finland"

通信作者:"Bobak, M (通讯作者),UCL, Res Dept Epidemiol & Publ Hlth, London, England."












关键词:Cognitive aging; Cognitive decline; Cross-cohort study; Socioeconomic status; Socioeconomic position

摘要:"Background and Objectives Cross-national research on cognitive aging inequality has largely concentrated on Western countries. It is unclear whether socioeconomic position (SEP) has similar effects on cognitive decline in emerging economies. We compared the association between life course SEP and cognitive function trajectories between China and England, the largest nation under state socialism and one of the oldest capitalist countries.Research Design and Methods This cross-cohort study examined participants aged 50 years and older from the China Health and Retirement Longitudinal Study (n = 12,832) and the English Longitudinal Study of aging (n = 8,875). Cognition z-scores were derived using comparable measures of memory and time orientation on 4 occasions. Life course SEP was self-reported by participants at baseline. Seven- to 8-year trajectories of cognition z-scores were estimated using latent growth curve modeling. Country- and gender-specific associations between childhood/adolescent deprivation, education, material wealth, and home ownership were evaluated in relation to model intercept (baseline level) and linear slope (annual rate of change) of cognition.Results After multivariable adjustment, education was positively associated with the greatest differences in baseline cognition across country and gender. Education was further linked to a slower rate of cognitive decline (z-score units per year); but compared with those with low education, Chinese men (b = 0.032) and women (b = 0.065) with high education had significantly slower declines than English men (b = -0.004) and women (b = 0.010) with high education.Discussion and Implications Despite substantial between-cohort differences in downstream and upstream determinants of dementia, education provided the greatest benefits to cognitive aging in England but particularly in China."

基金机构:"European Commission [667661, 857340, 857560]; European Research Council under the European Union's Horizon 2020 research and innovation program [101019329]; Strategic Research Council within the Academy of Finland [352543-352572, 308247]; Jane and Aatos Erkko Foundation; Max Planck Society; University of Helsinki; City of Helsinki; City of Vantaa; City of Espoo"

基金资助正文:"M. Ruiz, P. Martikainen, and M. Bobak received funding from a European Commission Horizon 2020 grant (#667661), as part of the Promoting Mental Wellbeing in the Aging Population: Determinants, Policies, and Interventions in European Cities (MINDMAP) research project. P. Martikainen was also supported by the European Research Council under the European Union's Horizon 2020 research and innovation program (grant agreement No. 101019329), the Strategic Research Council within the Academy of Finland grants for ACElife (#352543-352572) and LIFECON (#308247), and grants to the Max Planck- University of Helsinki Center from the Jane and Aatos Erkko Foundation, the Max Planck Society, University of Helsinki, and Cities of Helsinki, Vantaa, and Espoo. M.R. and M.B. have also been supported by European Commission Horizon 2020 grants (#857340, #857560) as part of the URBAN X and CETOCOEN Excellence research projects."